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Releases: epam/Indigo

Indigo-1.34.0

21 Aug 13:04
7a99033
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Features

  • #2899 - Peptide sequence should be auto-deceted at insert
  • #2958 - Map molfile monomers onto library monomers on import
  • #2967 - Support for marking of nucleotide components
  • #2952 - Expand c api to return CIP labels

Bugfixes and improvements

  • #2929 - Isoelectric Point calculation formula seems to be wrong
  • #2964 - System loads base as sugar
  • #2985 - Incorrect Implementation of PKA calculation
  • #2926 - Atom weights in indigo should be updated according to last IUPAC data
  • #2936 - System doesn't calculate melting temperature for mix of nucleotides/nucleosides and unsplit nucleotides/unsplit nucleosides
  • #2965 - System shouldn't allow to export molecules to 3-letter sequence format
  • #2989 - Export (and import) of sequence of nucleosides to HELM works wrong (doesn't work for import)
  • #2993 - System shouldn't consider closing bracket as part of name
  • #2998 - Input fields for ion concentration and oligonucleotides become inactive after entering excessively long number
  • #2970 - Rendering CIP labels breaks the generated svg for firefox
  • #3014 - Wrong bingo-postgres-linux version

Full Changelog: indigo-1.33.0-rc.1...indigo-1.34.0

Indigo-1.33.0

15 Aug 15:54
a2bcb5e
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Features

  • #2890 - Conda support
  • #2835 - Loading HELM with monomers with multi-character IDs without brackets
  • #2836 - Loading monomer NOT from the library as Unknown monomers (in the same manner as it works in IDT)

Bugfixes and improvements

  • #2933 - Melting temperature calculation works wrong
  • #2748 - Substituents are displayed backwards if appearing on the left of the molecule
  • #2934 - Melting temperature should not be defined for one RNA/DNA nucleotide chain lenght
  • #2927 - Molecule formula atom order wrong
  • #522 - core: replace Obj with standard smart pointer
  • #2937 - System doesn't calculate melting temperature for mix of nucleotides/nucleosides and phosphates
  • #2720 - Reaction SMILES lossily handles enhanced stereochemistry
  • #2968 - Melting temperature calculation works wrong
  • #2969 - Export of unknown for Ketcher monomers works wrong
  • #2923 - System doesn't substract from mass of monomer mass of leaving group atom(s) if an attachment point is occupied
  • #2966 - Load from HELM doesn't work for two side chain connected sequences
  • #2986 - Don't calculate Melting temperature for one pair of double stranded DNA/RNA nucleotides

Full Changelog: indigo-1.32.0-rc.1...indigo-1.33.0

Indigo-1.32.0

18 Jun 16:29
981e316
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Features

  • #2767 - Add support for Postgres 17
  • #1970 - New text entities in KET-format
  • #2843 - Support of "HELM alias" property for monomers
  • #2844 - Support for "Modification Type" property of monomers
  • #2870 - Add suuport for flip expanded monomer
  • #2840 - Add InChI key method to cpp api

Bugfixes and improvements

  • #2805 - Saving of 3:3 reaction to SDF v2000 causes exception: Convert error! core: <reaction> is not a base molecule
  • #2781 - Ketcher fails to save structure in MOL V3000 format when encountering custom attachment labels like “Ch”
  • #2851 - Macromolecule property Molecular mass wrong calculation
  • #2772 - Saving monomers to SDF v3000 works wrong - system saves every monomer template for every monomer on the canvas
  • #2860 - Copy to clipboard doesn't work if Multi-Tailed Arrow present on the canvas
  • #2858 - Export to any format doesn't work. System throw exception
  • #2047 - Saved Ellipse and Line Shapes in CDX, CDXML, Base 64 CDX formats are not correctly displayed after opening
  • #2868 - Indigo use wrong rotate parameter name KET files
  • #2867 - API calculateMacroProperties does not allow to pass parameters for UPC and NAC
  • #2859 - System wrongly reverse reaction order on Calculated Values dialog (and thus - values are wrong)
  • #2462 - Can't save a reaction with Multi-Tailed Arrow to Daylight SMARTS format
  • #2892 - API calculateMacroProperties does not work if only molecule passed as a parameter without monomers
  • #2888 - Unable to export single expanded monomer to SVG Image, system throws error: array: invalid index 0
  • #1679 - System ignores carrige return in text blocks in loaded CDX
  • #1683 - System shifts text label to the right
  • #2897 - Calculated Values doesn't work if reaction arrow overlaps reactant bounding box
  • #2931 - Calculated values doesn't work for "rich" monomer chain
  • #2917 - Molecular mass and Molecular formula are not calculated for Molecule (custom CHEM)
  • #2939 - System doesn't calculate melting temperature for GC nucleotides pair
  • #2930 - System shouldn't count bases that are not part of a nucleotide/nucleoside as RNA/DNA
  • #2947 - System "caches" PNG/SVG of canvas and stops reflect rotation/flip chanages if any
  • #2987 - Melting temperature value missed if UPC or NAC value set to zero
  • #2946 - Non-standard connections cause chain break in macromolecule properties calculation
  • #2902 - Indigo does not calculate properties for Peptides tab if Phosphate is missing in mixed chain
  • #2903 - Indigo fails to calculate properties when two chains are connected via a microstructure
  • #2904 - Indigo fails to calculate properties when two chains are connected via a CHEM
  • #2905 - Incorrect Calculate Properties result when monomers are connected via not a R2-R1

Full Changelog: indigo-1.31.0-rc.1...indigo-1.32.0

Indigo-1.31.0

17 Jun 15:56
13bb95f
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Features

  • #2788 - Support for PNG/SVG export of expanded monomers

Bugfixes and improvements

  • #2150 - Can't save a schema with some elements from Periodic Table in PNG and SVG format
  • #425 - Smiles with attachment points is not read correctly (valences are wrong)
  • #2747 - Incorrect substituent position
  • #1680 - System can't load CDX with (unsupported) brackets inside
  • #1631 - Add/Remove hydrogens changes Radical value from Diradical (triplet) to Diradical (singlet)
  • #2755 - Error occurs on click of "Remove Explicit Hydrogens" in reaction
  • #1686 - System shows positive charge modificator as extra + in addition to charge modified molecule
  • #2810 - Unnecessary rearrangment of cdxml reaction
  • #2807 - Missing label from cdxml
  • #2801 - Can't render reactions which contain brackets
  • #2778 - Can't render fragments with multiple external connections
  • #2815 - CIP labels are not rendered
  • #2591 - Reagents are repositioned above the reaction arrow after saving and loading RXN V2000/V3000 files
  • #2832 - Load from clipboard ignores RNA/DNA/PEP switcher and always loads DNA ambiguous bases even if RNA mode switched on
  • #2845 - Export to PNG/SVG works wrong for labels
  • #2722 - Monomer could be saved to RDF V3000 format but can't be loaded back - exception

Full Changelog: indigo-1.30.0-rc.1...indigo-1.31.0

indigo-1.32.0-rc.1

01 May 08:17
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indigo-1.32.0-rc.1 Pre-release
Pre-release

What's Changed

  • #2868 Indigo use wrong rotate parameter name KET files
  • #2867 API calculateMacroProperties does not allow to pass parameters for UPC and NAC
  • #2860 Copy to clipboard doesn't work if Multi-Tailed Arrow present on the canvas
  • #2859 System wrongly reverse reaction order on Calculated Values dialog (and thus - values are wrong)
  • #2858 Export to any format doesn't work. System throw exception
  • #2851 Macromolecule property Molecular mass wrong calculation
  • #2844 Support for "Modification Type" property of monomers
  • #2843 Support of "HELM alias" property for monomers
  • #2840 Add InChI key method to cpp api
  • #2805 Saving of 3:3 reaction to SDF v2000 causes exception: Convert error! core: is not a base molecule
  • #2781 Ketcher fails to save structure in MOL V3000 format when encountering custom attachment labels like “Ch”
  • #2772 Saving monomers to SDF v3000 works wrong - system saves every monomer template for every monomer on the canvas (geometry progression)
  • #2767 - Add support for Postgres 17
  • #2462 Can't save a reaction with Multi-Tailed Arrow to Daylight SMARTS format
  • #2047 Saved Ellipse and Line Shapes in CDX, CDXML, Base 64 CDX formats are not correctly displayed after opening
  • #1970 - New text entities in KET-format
  • #1686 System shows positive charge modificator as extra + in addition to charge modified molecule
  • #1683 System shifts text label to the right
  • #1679 System ignores carrige return in text blocks in loaded CDX
  • #2870 Add support for flip expanded monomer

Full Changelog: indigo-1.31.0-rc.2...indigo-1.32.0-rc.1

indigo-1.31.0-rc.2

29 Apr 08:51
4c82cbb
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What's Changed

  • #2591 Reagents are repositioned above the reaction arrow after saving and loading RXN V2000/V3000
  • #2832 Load from clipboard ignores RNA/DNA/PEP switcher and always loads DNA ambiguous bases even if RNA mode switched on by
  • #2845 Export to PNG/SVG works wrong for labels
  • #2722 Monomer could be saved to RDF V3000 format but can't be loaded back - exception

Full Changelog: indigo-1.31.0-rc.1...indigo-1.31.0-rc.2

indigo-1.30.1

06 May 07:35
5286cc7
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Indigo 1.30.1

Released 2025-04-17

Features

  • 2790 Support of "expanded" monomer option

Bugfixes and improvements

  • 2513 Elliptical arrows can not be saved to the png
  • 2412 User can't correctly save (or make a layout) to RDF/RXN reaction several products or with separate positioned molecules
  • 2746 Incorrect phosphorus valence
  • 2708 Export to SMILES works wrong if loaded from MOL
  • 2707 Atom Query feature export: System lost MOST "Substitution count" values
  • 2702 Export molecule which contains atom with five neighbors and stereo-bond cause error
  • 2704 System losts one stereo label if load from MOL
  • 2699 R Group logic condition is wrong if loaded from MOL
  • 2816 Format recognition order of content from clipboard should be changed for Sequence mode canvas
  • 2818 Library ambiguius RNA bases loaded from HELM as bases with % label
  • 2826 Unable to load ambiguous RNA and ambiguous DNA monomers with same name from HELM

Full Changelog: indigo-1.29.0...indigo-1.30.1

indigo-1.30.0

22 Apr 08:43
9ac0e34
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What's Changed

Features

  • #2790 - Support of "expanded" monomer option

Bugfixes and improvements

  • #2741 - Image missing stereochemistry information when using abbreviations
  • #2513 - Elliptical arrows can not be saved to the png by
  • #2412 - User can't correctly save (or make a layout) to RDF/RXN reaction several products or with separate positioned molecules
  • #2746 - Incorrect phosphorus valence
  • #2708 - Export to SMILES works wrong if loaded from MOL
  • #2707 - Atom Query feature export: System lost MOST "Substitution count" values
  • #2702 - Export molecule which contains atom with five neighbors and stereo-bond cause error
  • #2704 - System losts one stereo label if load from MOL
  • #2699 - R Group logic condition is wrong if loaded from MOL
  • #2816 - Format recognition order of content from clipboard should be changed for Sequence mode canvas
  • #2818 - Library ambiguius RNA bases loaded from HELM as bases with % label
  • #2826 - Unable to load ambiguous RNA and ambiguous DNA monomers with same name from HELM

Full Changelog: indigo-1.29.0...indigo-1.30.0

indigo-1.29.0

26 Mar 14:29
f10e024
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What's Changed

Features

  • #1844 - Implement GenBank/GenPept sequences import
  • #2552 - "Calculate Properties" for macromolecules
  • #2713 - Support for the star atom (*)

Bugfixes and improvements

  • #2739 - Wrong stereochemistry when reading cdxml reaction
  • #2744 - Indigo ignores alternate name for templates in MOL v3000
  • #2716 - Valid CXSMILES rejected
  • #2732 - V2000 Mol file loader skips essential SGroup line in certain cases
  • #2589 - Jump on uninitialised value
  • #2763 - System should ignore spaces before line indexes on GenBank/GenPept sequences import
  • #2798 - Peptide sequence not pasting directly on canvas

Full Changelog: indigo-1.28.0-rc.1...indigo-1.29.0

Indigo-1.28.0

13 Feb 10:52
08439ea
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What's Changed

Bugfixes

  • #2313 - Indigo functions doesn't work if ambiguous monomer present on the canvas
  • #2435 - Export of ambiguous monomers to Sequence/FASTA doesn't work for mixed ambiguous monomers
  • #2324 - System loads DNA bases instead of RNA ones during IDT import
  • #2387 - After opening a saved HELM file, microstructure name F1 turns into Mod0
  • #2062 - HELM loader ignores repeating token
  • #2332 - Error message should use "ambiguous monomer" instead of "variant monomer"
  • #2338 - System loads HELM inline SMILES phosphate as base (RNA1{R[P%91(O)(O)=O.[*:1]%91 |$;;;;_R1$|]}$$$$V2.0)
  • #2436 - System should report an error if we have one or more monomers on the canvas don't have mapping for them in case of export to Sequence/FASTA
  • #2427 - Import of unsplit monomers from HELM doesn't work
  • #2041 - Monomer could be saved to RXN V3000 format but can't be loaded back - exception
  • #2137 - An error occurred while saving the unresolved nucleotides and arrow in the RXN3000 format
  • #2195 - Indigo functions doesn't work if query atom and monomer on the canvas at the same time
  • #2126 - An error occurred while saving the nucleotide and arrow in the RXN2000 format
  • #2330 - Error diagnostic is not clear in case of wrong percent value type
  • #2622 - Saving to MOL 3000 cause template data loss that causes wrong export to HELM
  • #2361 - Wrong error message if SMILES phosphate has lack of attachemt point
  • #2359 - System loads HELM even it it has wrong connection section (PEPTIDE1{[DACys]}|PEPTIDE2{C}$PEPTIDE1,PEPTIDE2,1:R1-1:R2$$$V2.0)
  • #2539 - Export of unknown monomer to HELM doesn't work
  • Revert "#2657 - Add ES6 options for WASM build (#2658)"

Full Changelog: indigo-1.27.0-rc.1...indigo-1.28.0