diff --git a/Lib/test/test_typing.py b/Lib/test/test_typing.py
index 8238c62f0715f8..b754703bd7a772 100644
--- a/Lib/test/test_typing.py
+++ b/Lib/test/test_typing.py
@@ -761,6 +761,16 @@ class A(Generic[T, P, U]): ...
         self.assertEqual(A[float, [range]].__args__, (float, (range,), float))
         self.assertEqual(A[float, [range], int].__args__, (float, (range,), int))
 
+    def test_paramspec_and_typevar_specialization_2(self):
+        T = TypeVar("T")
+        P = ParamSpec('P', default=...)
+        U = TypeVar("U", default=float)
+        self.assertEqual(P.__default__, ...)
+        class A(Generic[T, P, U]): ...
+        self.assertEqual(A[float].__args__, (float, ..., float))
+        self.assertEqual(A[float, [range]].__args__, (float, (range,), float))
+        self.assertEqual(A[float, [range], int].__args__, (float, (range,), int))
+
     def test_typevartuple_none(self):
         U = TypeVarTuple('U')
         U_None = TypeVarTuple('U_None', default=None)
diff --git a/Lib/typing.py b/Lib/typing.py
index babe3c44d9dc55..5b76a5ef3aa6f0 100644
--- a/Lib/typing.py
+++ b/Lib/typing.py
@@ -1100,7 +1100,7 @@ def _paramspec_prepare_subst(self, alias, args):
     params = alias.__parameters__
     i = params.index(self)
     if i == len(args) and self.has_default():
-        args = [*args, self.__default__]
+        args = (*args, self.__default__)
     if i >= len(args):
         raise TypeError(f"Too few arguments for {alias}")
     # Special case where Z[[int, str, bool]] == Z[int, str, bool] in PEP 612.
diff --git a/Misc/NEWS.d/next/Library/2025-09-13-12-19-17.gh-issue-138859.PxjIoN.rst b/Misc/NEWS.d/next/Library/2025-09-13-12-19-17.gh-issue-138859.PxjIoN.rst
new file mode 100644
index 00000000000000..a5d4dd042fcd5b
--- /dev/null
+++ b/Misc/NEWS.d/next/Library/2025-09-13-12-19-17.gh-issue-138859.PxjIoN.rst
@@ -0,0 +1 @@
+Fix generic type parameterization raising a :exc:`TypeError` when omitting a :class:`ParamSpec` that has a default which is not a list of types.